Gold Standard Preservation provides clinical machine perfusion coverage for transplant centers and OPO partners seeking reliable execution, standardized workflows, and experienced interpretation of perfusion behavior. We support both normothermic and hypothermic machine perfusion for livers and kidneys, with a focus on maintaining stability, reducing variability, and generating clear, actionable performance documentation for the transplant team.

Liver machine perfusion

• Normothermic liver perfusion (NMP): Controlled physiologic support to assess viability and reduce variability in organ performance prior to implant.

• Hypothermic liver perfusion (HMP/HOPE-style workflows where applicable): Metabolic downshift strategies focused on oxygenation and mitochondrial support at lower temperatures.

Kidney machine perfusion

• Hypothermic kidney perfusion (HMP): Optimization of flow, resistance, and perfusate management to support microcirculation and reduce preservation-related stress.

• Normothermic kidney perfusion (where utilized): Physiologic support and assessment under warmer conditions when program protocols indicate.

What makes our perfusion support different?

Perfusion is not just operating a device; it is managing an organ in a dynamic physiologic state outside the body. Our teams are trained to interpret how organs behave across temperature transitions and how that behavior manifests in hemodynamics, metabolic trends, and perfusate chemistry.

We focus on:

• Trajectories, not single data points (e.g., lactate kinetics, pH/base excess trends, resistance/flow behavior)

• Temperature-aware physiology

Protocol-driven perfusate and acid-base strategy

• Hemodynamic tuning with attention to endothelial and microcirculatory behavior

• Structured response to instability (rising resistance, worsening acidosis, metabolic stagnation)

• Clear documentation of what changed, why it changed, and what happened next